Blogs

From Rosetta@home to Folding@home Let’s start with the main principle. Rosetta@home is only predicting the molecular structure of synthetic drugs capable of Binding Covid-19 outer spike-in protein, which can be imagined as similar to the photographic technique in photography. Rosetta can statically predict the characteristics of a particular protein, but it cannot predict how that protein molecule will function under the evolution of time. Because there will be potential differences between molecules that generate electromagnetic forces, and all the constituent elements within the molecule will interact with each other to create motion over time, when we design a synthetic drug in Rosetta that can bind the SARS-COV-2 virus, we need to enter the testing phase to see if the drug can bind to the viral protein stably, because the predicted structure is static, we cannot know whether the protein structure can bind well to the viral protein under the interaction motion, here Folding@home comes in handy, it is similar to shooting a motion picture in photography, we can get the static protein structure chain from Rosetta@home, and then simulate in Folding@home whether that protein binds well to the viral protein over time to produce resistance to the virus. ...

Images From Openebs Preface About OpenEBS OpenEBS is an open source storage project running on Kubernets, in line with the CAS (Container Attached Storage) architecture. All of its components run at the user level and belong to the cloud-native distributed file system on k8s. OpenEBS file system provides the following categories of features , each feature can be used in a particular environment solution . cStor: supports fault tolerance, high availability, replica copy, snapshot, clone, etc. Its backend is supported by ZFS. ...

The initial version of the www.cineneural.com website is now online, the main website is hosted on a Raspberry Pi 4 cluster built by myself, and the main function of the official website is to provide an entry point for medical image processing. The main function of the website is to provide a portal for medical image processing. To Do list: encrypt all traffic. increase the network stability of cloudflare <-> Home Raspberry Pi. ...

NVIDIA CLARA DISCOVERY Eco Nvidia’s entry into the medical field. From the cover we can see a ring structure: Natural Language -> Viral Gene Sequence -> Viral Protein Structure -> New Drug Docking with Viral Protein -> Molecular Docking Dynamics Simulation -> Clinical Trial of Drug Candidate Detecting Medical Images of Patient’s Lungs -> Natural Language Introduction At the Nvidia GTC 2020 Fall Conference, Nvidia announced the NVIDIA CLARA DISCOVERY drug development framework, which aims to accelerate the progress of global drug development. With the news of Nvidia’s acquisition of ARM before, I realized that Nvidia has the ambition to rule the edge computing field in the future. Not surprisingly, this GTC conference Nvidia updated many product lines, including large to data center computing module BlueField-2, small to edge field jetson Nano 2G, the most exciting for me is still ** CLARA DISCOVERY**, because my own short-term goal is how to use edge computing in the medical field, such as individuals can calculate the current status of their own diseases through edge computing devices combined with their own diagnostic data obtained from hospital examinations, as well as judgmental detection of Covid-19 CT, ChestXRay. ...

Last night I went to see Fan Jia Ming Organ Recital, the first half of the concert was a Western baroque organ pieces, the second half of the concert had the player’s own composition and adaptation of the national style of oriental music, through the organ to depict the East of this idea of the unity of heaven and man, oriental music focuses on the mood, while Western music focuses on the diversity of musical weaving, I must say that the player is very elegant, himself I took a few photos for my memory. ...